Today I started to play the adventure game "Return to Mysterious Island." So far, great game - looks great, sounds great, good premise, like the interface. But one big problem - it's first person, and the screen moves with my cursor. It gives me motion sickness (or more specifically, simulator sickness). I really want to play this game, but can only handle it in short spurts or the headaches and nausea will persist long after I stop. This is the reason I don't play first person shooters. Sadly, more adventure games are getting going the "realistic" route as well.
I found a great article on simulator sickness, found here.